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Buy Lipitor 20mg Online is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipid levels. For the prevention of cardiovascular disease, statins are a first-line treatment. It is taken by mouth.
Common side effects include joint pain, diarrhea, heart burn, nausea, and muscle pains. Serious side effects may include rhabdomyolysis, liver problems, and diabetes. Use during pregnancy may harm the baby. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol.
Atorvastatin was patented in 1986 and approved for medical use in the United States in 1996. It is available as a generic medication. In the United States, the wholesale cost per month is about 3.80 USD as of 2018. In the United Kingdom, it costs the NHS about £0.70 per month as of 2018. In 2016, it was the 3rd most prescribed medication in the United States, with more than 96 million prescriptions.
The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease:
Hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce total cholesterol, LDL-C, apo-B, triglycerides levels, and CRP as well as increase HDL levels.
Heterozygous familial hypercholesterolemia in children
Homozygous familial hypercholesterolemia
Hypertriglyceridemia (Fredrickson Type IV)
Primary dysbetalipoproteinemia (Fredrickson Type III)
Primary prevention of heart attack, stroke, and need for revascularization procedures in people who have risk factors such as age, smoking, high blood pressure, low HDL-C, and a family history of early heart disease, but have not yet developed evidence of coronary artery disease.
Secondary prevention of myocardial infarction, stroke, unstable angina, and revascularization in people with established coronary artery disease.
Myocardial infarction and stroke prevention in people with type II diabetes
Studies suggest that high-dose statin therapy may play a plaque-stabilizing role in people with acute coronary syndrome and thrombotic stroke.
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Statins, including atorvastatin, have a small, but significant beneficial effect on preventing the loss of kidney function and on reducing loss of protein in urine in people with cardiovascular disease.
Preoperative treatment with statins, including atorvastatin, does not prevent acute kidney injury in persons having cardiac surgery.
Atorvastatin may be used in combination with bile acid sequestrants and ezetimibe to increase the reduction in cholesterol levels. However, It is not recommended to combine statin medication treatment with certain other cholesterol-lowering medications, particularly fibrates, because this may increase the risk of myopathy-related adverse effects.
While many statin medications should be administered at bedtime for optimal effect, atorvastatin can be dosed at any time of day, as long as it is continually dosed once daily at the same time.