Description
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N-Ethylpentylone (also known as bk-EBDP, βk-EBDP, and ephylone) is a novel stimulant-entactogen substance of the cathinone class. Ephylone is chemically related to pentylone and belongs to a group of compounds known as the substituted cathinones. Little is known about its pharmacology, although it likely produces its effects by increasing levels of serotonin, dopamine, and norepinephrine in the brain.
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Ephylone was developed in the 1960s by Boehringer Ingelheim as a central nervous system stimulant, although it never became marketed. Reports of recreational use first appeared in late 2015. Since then, its prevalence has steadily risen, particularly at dance music festivals where it appears as an adulterant or counterfeit for MDMA.Ephylone has been linked to numerous hospitalizations and overdose deaths.
User reports indicate that ephylone produces a mixture of classic stimulant and entactogenic effects resembling those of MDMA, methylone and cocaine. Typical effects include stimulation, disinhibition, increased libido, compulsive redosing, and euphoria. Unlike similar substances, however, ephylone is reported to be very long lasting when taken in larger doses. The significance of this is not known, although it may indicate that it has a different toxicity profile compared to other stimulants.
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Ephylone is sold online as a research chemical alongside other synthetic cathinones like ethylone and dibutylone. Due to the lack of research, it is highly advised to use harm reduction practices if using this substance.
Synthetic cathinones were first synthesized in the late 1920s, starting with methcathinone and mephedrone. However, they did not find medical use due to their side effects. In the early 2000s, synthetic cathinones began to be sold in “head” shops and online as designer drugs, also known as research chemicals and “legal highs”. Their quasi-legality and ability to substitute for traditional stimulants like cocaine or amphetamine made them popular in certain demographics. Due to a history of being falsely marketed as bath salt products, they are referred in the media as “bath salts.”
